Adding is-url class with importent, as W3C says all URLs are LTR therefore importent makes sense in this case

src/Orchard.Web/Core/Settings/Views/EditorTemplates/Parts.Settings.SiteSettingsPart.cshtml

@@ -16,7 +16,7 @@
     </div>
     <div>
         <label for="@Html.FieldIdFor(m => m.BaseUrl)">@T("Base URL")</label>
-        @Html.TextBoxFor(m => m.BaseUrl, new { @class = "text medium" })
+        @Html.TextBoxFor(m => m.BaseUrl, new { @class = "text medium is-url" })
         <span class="hint">@T("Enter the fully qualified base URL of the web site.")</span>
         <span class="hint">@T("e.g., http://localhost:30320/orchardlocal, http://www.yourdomain.com")</span>
     </div>

src/Orchard.Web/Modules/Orchard.Autoroute/Views/EditorTemplates/Parts.Autoroute.Edit.cshtml

@@ -21,9 +21,9 @@
     <fieldset class="permalink">
         <label>@T("Permalink")</label>
         @if (Model.Settings.AllowCustomPattern) {
-            <span class="permalink-definition" dir="ltr">
+            <span class="permalink-definition">
                 <span>@Url.MakeAbsolute("/")@urlPrefix</span>
-                <span>@Html.TextBoxFor(m => m.CurrentUrl, new { @class = "text" })</span>
+                <span>@Html.TextBoxFor(m => m.CurrentUrl, new { @class = "text is-url" })</span>
             </span>
             <span class="hint">@T("Save the current item and leave the input empty to have it automatically generated using the pattern {0} e.g., {1}", defaultPattern.Name, defaultPattern.Description)</span>
         }

src/Orchard.Web/Themes/TheAdmin/Styles/site.css

@@ -1095,12 +1095,16 @@ html.dyn #submit-pager, html.dyn .apply-bulk-actions-auto { display:none; }
     margin-left:0;
     margin-right:2em;
     width:350px;
+    direction: ltr;
 }
 .permalink input.text:focus {
     background:#FFF;
     border-color:#666d51;
     border-style:solid;
 }
+.is-url {
+    direction: ltr !important;
+}
 /* Routable and Containers (Core) */
 .with-checkbox .checkbox-and-label { /* todo: (heskew) routable should be changed to use this too */
     margin-left:10px;